Diseases

Arthritis Medications: Finding the Right Treatment for Your Pet

There usually isn't one best arthritis medication. Learn how veterinarians build a multimodal plan that keeps pets comfortable and active.

What's the best arthritis medication? Usually, there isn't just one. Learn how multimodal pain management combines medications, weight management, rehabilitation, and supplements—and why safety and realistic goals matter.

By Dr. Rene'8 min readJul 30, 2026Vet reviewed Jul 30, 2026
Then-and-now comparison cover showing dogs and cats before and after developing signs of joint pain, used as the Arthritis Learning Series cover art.

Quick answer

There usually isn't a single best arthritis medication. Because arthritis is a lifelong disease, veterinarians typically use multimodal pain management—combining weight management, exercise, rehabilitation, medications such as NSAIDs or monoclonal antibody injections like Librela® and Solensia®, supplements, and home modifications. Every plan is individualized, requires veterinary monitoring, and should never include human pain medications unless specifically directed.

In this article you'll learn

  • Why arthritis treatment usually requires more than one therapy
  • What factors shape your pet's individual treatment plan
  • How arthritis treatment options have advanced in recent years
  • What realistic treatment success actually looks like
  • Why veterinary monitoring and bloodwork matter
  • Which human pain medications are dangerous for pets

One of the biggest questions I hear from pet owners is:

"What's the best arthritis medication?"

The honest answer is...

There usually isn't just one.

Arthritis is a lifelong disease, and successful treatment often requires a combination of therapies working together. That's why veterinarians frequently use a multimodal pain management approach—combining weight management, exercise, rehabilitation, medications, supplements, and home modifications to keep pets as comfortable and active as possible.

Think of arthritis treatment like building a team.

Every member has a different job.

Some medications reduce inflammation.

Others block pain signals.

Some improve joint function.

Others help your pet move more comfortably so they can rebuild muscle and stay active.

Our goal isn't simply to reduce pain for today.

Our goal is to help your pet enjoy many more comfortable years doing the things they love.

There Is No "One-Size-Fits-All" Treatment

Every pet experiences arthritis differently.

A young Labrador with hip dysplasia may need a very different treatment plan than a 15-year-old cat with arthritis affecting multiple joints.

Your veterinarian will consider many factors, including:

  • Your pet's age
  • Weight and body condition
  • Which joints are affected
  • How severe the arthritis is
  • Other medical conditions (such as kidney or liver disease)
  • Current medications
  • Lifestyle and activity level
  • Your family's goals for treatment

For some pets, a single medication may provide excellent relief.

For others, combining several treatments produces the best results.

Infographic titled There Isn't Just One Answer: A Team Approach to Arthritis Care — a golden retriever surrounded by six circles for medications, weight management, physical rehabilitation, omega-3 and joint supplements, home modifications, and exercise and daily movement, all connected to a central multimodal pain management hub.
Better together — combining therapies means less pain, more mobility, and more good days.

Arthritis Treatment Has Changed Dramatically

If your previous dog had arthritis 15 years ago, today's options may surprise you.

Veterinary medicine has advanced tremendously.

In addition to traditional anti-inflammatory medications, we now have therapies that specifically target pain pathways, injectable monoclonal antibody treatments like Librela® for dogs and Solensia® for cats, rehabilitation programs, and a growing understanding of how nutrition and body condition influence chronic joint pain.

That means many pets are staying comfortable and active far longer than they could have just a decade ago.

The Goal Isn't to Eliminate Every Ache

One of the most important conversations I have with families is setting realistic expectations.

Because arthritis is a chronic, progressive disease, we usually can't make an arthritic joint completely normal again.

What we can often do is dramatically improve comfort and function.

Success may look like:

  • Going on longer walks again
  • Climbing stairs more comfortably
  • Jumping onto favorite furniture
  • Playing with toys
  • Greeting family at the door
  • Sleeping more comfortably
  • Getting up without struggling
  • Enjoying everyday life again

Those improvements often mean far more than a perfect X-ray ever could.

Safety Comes First

Every medication has potential benefits and potential risks.

That's why arthritis medications should always be chosen and monitored by your veterinarian.

Some pets require routine bloodwork.

Others may need dose adjustments or changes over time.

Never start, stop, or combine medications without speaking with your veterinary team, and never give human pain medications unless your veterinarian specifically instructs you to do so.

Many medications that are safe for people—including ibuprofen, naproxen, and acetaminophen—can be dangerous or even fatal to pets.

The Good News

Today, we have more options than ever before to help dogs and cats with arthritis.

Whether your pet benefits most from an NSAID, Librela®, Solensia®, rehabilitation, weight management, supplements, or a combination of treatments, the goal is always the same:

Less pain. More movement. More good days together.

Frequently asked questions

Tags:arthritis medicationsNSAIDs for dogsLibrelaSolensiamultimodal pain managementjoint supplementsarthritis treatment for catspain relief for dogshuman pain medication toxicitychronic pain management

Educational only. This article is not a substitute for veterinary care. If your pet is unwell, please contact your veterinarian.

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